5946 Results for "

Pongamia pinnata (L.) Pierre

" in MedChemExpress (MCE) Product Catalog:
Products (5946)

5946 Results for "Pongamia pinnata (L.) Pierre" in MCE Product Catalog:

666
Acetylcysteine
Acetylcysteine
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666 Publications Verification
Referencia número: HY-B0215
No. CAS: 616-91-1
Synonyms: N-Acetylcysteine; N-Acetyl-L-cysteine; NAC
Category:  

Ketones, Aldehydes, Acids Endogenous metabolite

Target:  

Reactive Oxygen Species (ROS) Endogenous Metabolite Apoptosis Ferroptosis Influenza Virus Disulfidptosis

Acetylcysteine (N-Acetylcysteine) is a mucolytic agent that can cross the blood-brain barrier, which reduces the thickness of the mucus. Acetylcysteine is a ROS inhibitor. Acetylcysteine is a cysteine precursor, prevents hemin-induced ferroptosis by neutralizing toxic lipids generated by arachidonate-dependent activity of 5-lipoxygenases. Acetylcysteine induces cell apoptosis. Acetylcysteine also has anti-influenza virus activities. In addition, Acetylcysteine ​​is the most stable form of cysteine ​​during drug delivery and can be used in disulfidptosis studies .
99
EIPA
EIPA
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99 Cited Publications
Referencia número: HY-101840
No. CAS: 1154-25-2
Pureza:  99.73%
Synonyms: L593754; MH 12-43; Ethylisopropylamiloride
Target:  

TRP Channel Prostaglandin Receptor Autophagy COX Na+/H+ Exchanger (NHE)

Áreas de investigación:  

Inflammation/Immunology Cancer

EIPA (L593754) is an orally active TRPP3 channel inhibitor with an IC50 of 10.5 μM. EIPA also enhances autophagy by inhibiting Na +/H +-exchanger 3 (NHE3). EIPA inhibits macropinocytosis as well. EIPA can be used in the research of inflammation and cancers, such as gastric cancer, colon carcinoma, pancreatic carcinoma .
99
EIPA hydrochloride
EIPA hydrochloride
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99 Cited Publications
Referencia número: HY-101840A
No. CAS: 1345839-28-2
Pureza:  98.31%
Synonyms: L593754 hydrochloride; MH 12-43 hydrochloride; Ethylisopropylamiloride hydrochloride
Target:  

TRP Channel Autophagy COX Prostaglandin Receptor Na+/H+ Exchanger (NHE)

Áreas de investigación:  

Inflammation/Immunology Cancer

EIPA (L593754) hydrochloride is an orally active TRPP3 channel inhibitor with an IC50 of 10.5 μM. EIPA hydrochloride also enhances autophagy by inhibiting Na +/H +-exchanger 3 (NHE3). EIPA hydrochloride inhibits macropinocytosis as well. EIPA hydrochloride can be used in the research of inflammation and cancers, such as gastric cancer, colon carcinoma, pancreatic carcinoma .
88
Genistein
Genistein
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88 Cited Publications
Referencia número: HY-14596
No. CAS: 446-72-0
Pureza:  99.82%
Synonyms: NPI 031L
Category:  

Anti-aging Plants Endogenous metabolite Human Gut Microbiota Metabolites Flavonoids Microorganisms Leguminosae Glycine max (L.) merr Sunscreen Phenols Polyphenols Cosmetic Research Disease Research Fields Glycyrrhiza uralensis Fisch. Cancer Isoflavones

Target:  

EGFR Autophagy Apoptosis Endogenous Metabolite

Genistein, a soy isoflavone, is a multiple tyrosine kinases (e.g., EGFR) inhibitor which acts as a chemotherapeutic agent against different types of cancer, mainly by altering apoptosis, the cell cycle, and angiogenesis and inhibiting metastasis.
88
Genistein (Standard)
Genistein (Standard)
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88 Cited Publications
Referencia número: HY-14596R
No. CAS: 446-72-0
Pureza:  99.31%
Synonyms: NPI 031L (Standard)
Category:  

Anti-aging Plants Endogenous metabolite Human Gut Microbiota Metabolites Flavonoids Leguminosae Glycine max (L.) merr Sunscreen Phenols Cosmetic Research Disease Research Fields Glycyrrhiza uralensis Fisch. Cancer

Target:  

Reference Standards EGFR Autophagy Apoptosis Endogenous Metabolite

Genistein (Standard) is the analytical standard of Genistein. This product is intended for research and analytical applications. Genistein, a soy isoflavone, is a multiple tyrosine kinases (e.g., EGFR) inhibitor which acts as a chemotherapeutic agent against different types of cancer, mainly by altering apoptosis, the cell cycle, and angiogenesis and inhibiting metastasis.
81
L-Ascorbic acid
L-Ascorbic acid
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81 Cited Publications
Referencia número: HY-B0166
No. CAS: 50-81-7
Synonyms: L-Ascorbate; Vitamin C
Category:  

Natural Products Neurological Disease Moringa oleifera Lam. Metabolic Disease Endocrine diseases Plants Endogenous metabolite Disease markers Moringaceae Nervous System Disorder Disease Research Fields

Target:  

Environmental Pollutants Endogenous Metabolite Calcium Channel Reactive Oxygen Species (ROS) Apoptosis

L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor . L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells .
81
L-Ascorbic acid sodium salt
L-Ascorbic acid sodium salt
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81 Cited Publications
Referencia número: HY-B0166A
No. CAS: 134-03-2
Synonyms: Sodium ascorbate; Sodium L-ascorbate; Vitamin C sodium salt
Category:  

Natural Products other families Plants Disease Research Fields Cancer

Target:  

Environmental Pollutants Apoptosis Endogenous Metabolite Calcium Channel Reactive Oxygen Species (ROS)

L-Ascorbic acid sodium salt (Sodium ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid sodium salt selectively inhibits Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid sodium salt is also a collagen deposition enhancer and an elastogenesis inhibitor .
79
L-NAME hydrochloride
L-NAME hydrochloride
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79 Cited Publications
Referencia número: HY-18729A
No. CAS: 51298-62-5
Synonyms: NG-Nitroarginine methyl ester hydrochloride
Target:  

NO Synthase

Áreas de investigación:  

Infection Neurological Disease Cancer

L-NAME hydrochloride inhibits NOS with an IC50 of 70 μM. L-NAME is a precursor to NOS inhibitor L-NOARG which has an IC50 value of 1.4 μM. L-NAME hydrochloride requires hydrolysis of the methyl ester by cellular esterases to become a fully functional inhibitor. L-NAME hydrochloride can be used to induce hypertension and preeclampsia models.
74
L-Ascorbic acid calcium dihydrate
L-Ascorbic acid calcium dihydrate
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74 Cited Publications
Referencia número: HY-B0166C
No. CAS: 5743-28-2
Synonyms: L-Ascorbate calcium dihydrate; Vitamin C calcium dihydrate
L-Ascorbic acid (calcium dihydrate) (L-Ascorbate (calcium dihydrate); Vitamin C (calcium dihydrate)) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
62
Reparixin L-lysine salt
Reparixin L-lysine salt
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62 Cited Publications
Referencia número: HY-15252
No. CAS: 266359-93-7
Pureza:  99.87%
Synonyms: Repertaxin L-lysine salt
Target:  

CXCR

Áreas de investigación:  

Inflammation/Immunology Endocrinology Cancer

Reparixin L-lysine salt is an allosteric inhibitor of chemokine receptor 1/2 (CXCR1/2) activation.
62
Norepinephrine
Norepinephrine
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62 Cited Publications
Referencia número: HY-13715
No. CAS: 51-41-2
Pureza:  99.61%
Synonyms: Levarterenol; L-Noradrenaline
Category:  

Cardiovascular Disease Phenols Polyphenols Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite Adrenergic Receptor Autophagy

Norepinephrine (Levarterenol; L-Noradrenaline) is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α1, α2, β1 receptors .
62
Norepinephrine hydrochloride
Norepinephrine hydrochloride
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62 Cited Publications
Referencia número: HY-13715A
No. CAS: 329-56-6
Pureza:  99.89%
Synonyms: Levarterenol hydrochloride; L-Noradrenaline hydrochloride
Category:  

Cardiovascular Disease Alkaloids Leguminosae Mimosa pudica Linn. Other Alkaloids Phenols Polyphenols Plants Disease Research Fields Endocrinology

Target:  

Adrenergic Receptor Autophagy Endogenous Metabolite

Norepinephrine (Levarterenol; L-Noradrenaline) hydrochloride is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α1, α2, β1 receptors .
62
Norepinephrine bitartrate monohydrate
Norepinephrine bitartrate monohydrate
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62 Cited Publications
Referencia número: HY-13715B
No. CAS: 108341-18-0
Pureza:  99.96%
Synonyms: Levarterenol bitartrate monohydrate; L-Noradrenaline bitartrate monohydrate
Category:  

Phenols Endogenous metabolite Disease Research Fields Endocrinology

Target:  

Adrenergic Receptor Autophagy Endogenous Metabolite

Norepinephrine (Levarterenol; L-Noradrenaline) bitartrate monohydrate is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α1, α2, β1 receptors .
62
Norepinephrine tartrate
Norepinephrine tartrate
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62 Cited Publications
Referencia número: HY-13715C
No. CAS: 51-40-1
Pureza:  99.76%
Synonyms: Levarterenol tartrate; L-Noradrenaline tartrate
Category:  

Cardiovascular Disease Phenols Polyphenols Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite Adrenergic Receptor Autophagy

Norepinephrine (Levarterenol; L-Noradrenaline) tartrate is a potent adrenergic receptor (AR) agonist. Norepinephrine tartrate activates α1, α2, β1 receptors .
55
L-Glutathione reduced
L-Glutathione reduced
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55 Cited Publications
Referencia número: HY-D0187
No. CAS: 70-18-8
Synonyms: GSH; γ-L-Glutamyl-L-cysteinyl-glycine
Category:  

Cardiovascular Disease Human Gut Microbiota Metabolites Microorganisms Neurological Disease Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:  

Endogenous Metabolite Reactive Oxygen Species (ROS) Ferroptosis

L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) is an endogenous antioxidant and is capable of scavenging oxygen-derived free radicals.
54
Flavopiridol
Flavopiridol
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54 Cited Publications
Referencia número: HY-10005
No. CAS: 146426-40-6
Pureza:  99.73%
Synonyms: HMR-1275; Alvocidib; L86-8275
Target:  

CDK Autophagy HIV Apoptosis

Áreas de investigación:  

Cancer

Flavopiridol (Alvocidib) is a broad spectrum and competitive inhibitor of CDKs, inhibiting CDK1, CDK2, CDK4 with IC50s of 30, 170, 100 nM, respectively.
54
Flavopiridol Hydrochloride
Flavopiridol Hydrochloride
0 Images
54 Cited Publications
Referencia número: HY-10006
No. CAS: 131740-09-5
Pureza:  99.73%
Synonyms: Alvocidib Hydrochloride; L86-8275 Hydrochloride; HMR-1275 Hydrochloride
Target:  

CDK Autophagy HIV

Áreas de investigación:  

Cancer

Flavopiridol Hydrochloride (Alvocidib Hydrochloride) is a broad inhibitor of CDK, competing with ATP to inhibit CDKs including CDK1, CDK2, CDK4 with IC50s of 30, 170, 100 nM, respectively.
40
Liothyronine sodium
Liothyronine sodium
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40 Cited Publications
Referencia número: HY-A0070
No. CAS: 55-06-1
Synonyms: Triiodothyronine sodium; 3,3',5-Triiodo-L-thyronine sodium; T3 sodium
Category:  

Monophenols Phenols Endogenous metabolite Disease Research Fields Endocrinology Cancer

Target:  

Thyroid Hormone Receptor Endogenous Metabolite

Liothyronine sodium is an active form of thyroid hormone. Liothyronine sodium is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively .
40
Liothyronine
Liothyronine
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40 Cited Publications
Referencia número: HY-A0070A
No. CAS: 6893-02-3
Synonyms: Triiodothyronine; 3,3',5-Triiodo-L-thyronine; T3
Category:  

Microorganisms Monophenols Ketones, Aldehydes, Acids Disease markers Endocrine diseases Phenols Endogenous metabolite Disease Research Fields Endocrinology

Target:  

Thyroid Hormone Receptor Endogenous Metabolite

Liothyronine is an active form of thyroid hormone. Liothyronine binds to thyroid hormone receptors TRα and TRβ with Kis of 2.33 and 2.29 nM for hTRα and hTRβ, respectively. Liothyronine also binds to PVR and blocks the interaction of TIGIT/PVR .
40
Liothyronine sodium hydrate
Liothyronine sodium hydrate
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40 Cited Publications
Referencia número: HY-A0070B
No. CAS: 345957-19-9
Synonyms: Triiodothyronine sodium hydrate; 3,3',5-Triiodo-L-thyronine sodium hydrate; T3 sodium hydrate
Category:  

Monophenols Phenols Endogenous metabolite Disease Research Fields Endocrinology Cancer

Target:  

Thyroid Hormone Receptor Endogenous Metabolite

Liothyronine sodium hydrate is an active form of thyroid hormone. Liothyronine sodium hydrate is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively .
Assay Types